Tuesday, January 8, 2008

24 new messages in 10 topics - digest

misc.consumers.frugal-living
http://groups.google.com/group/misc.consumers.frugal-living?hl=en

misc.consumers.frugal-living@googlegroups.com

Today's topics:

* Lead in vacuum cleaner cord? - 8 messages, 6 authors
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/ecb46a599d841f30?hl=en
* Looking Forward - 1 messages, 1 author
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/78cb5b0089fdc03b?hl=en
* how to catch a clever mouse? - 5 messages, 3 authors
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/bc8fd4ec8439afb6?hl=en
* Chinese Exports Safe - 1 messages, 1 author
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/656ddf21b6fa6b07?hl=en
* Best frugal technology deal you've gotten - 4 messages, 4 authors
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/432b1da46fece658?hl=en
* Experimental Drugs. Your Moral Compass? - 1 messages, 1 author
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/b3c607adfe84a43e?hl=en
* www.globwholesale.com Discount wholesale NBA SPORT SHOES, UGG BOOTS, LRG
JEANS - 1 messages, 1 author
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/3ebe692339a1d1af?hl=en
* Donation Question - 1 messages, 1 author
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/ede7dc79ef5b9e1e?hl=en
* Web 2.0-Whats The Next Big Thing? See What Yahoo Said ! - 1 messages, 1
author
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/e6966aae817e94d9?hl=en
* Tips on living cheaply in the Philadelphia region - 1 messages, 1 author
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/7c4d094a72698045?hl=en

==============================================================================
TOPIC: Lead in vacuum cleaner cord?
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/ecb46a599d841f30?hl=en
==============================================================================

== 1 of 8 ==
Date: Tues, Jan 8 2008 12:27 pm
From: "Rod Speed"


me@privacy.net wrote:

> I recently bought a small Dirt Devil Dynamite vacuum.
> After reading the manual carefully I found this warning:

> WARNING: THE CORDS, WIRES AND/OR CABLES SUPPLIED WITH
> THlS PRODUCT CONTAINS CHEMICALS, INCLUDING LEAD OR LEAD
> COMPOUNDS, KNOWN TO THE STATE OF CALIFORNIA TO CAUSE
> CANCER AND BIRTH DEFECTS OR OTHER REPRODUCTIVE HARM.
> WASH HANDS AFTER USING

> Took the unit back and bought a similar vac form
> Hoover.... but had the SAME warning in the manual!

> What gives?

Just the usual mindless silly stuff imposed by legislation, in this case california.

> Why would they market/sell a unit with such a toxic chemical in it?

They dont, lead isnt a toxic chemical in that sense.


== 2 of 8 ==
Date: Tues, Jan 8 2008 12:30 pm
From: Dennis


On Tue, 08 Jan 2008 13:59:01 -0600, me@privacy.net wrote:

>I recently bought a small Dirt Devil Dynamite vacuum.
>After reading the manual carefully I found this
>warning:
>
>WARNING: THE CORDS, WIRES AND/OR CABLES SUPPLIED WITH
>THlS PRODUCT CONTAINS CHEMICALS, INCLUDING LEAD OR LEAD
>COMPOUNDS, KNOWN TO THE STATE OF CALIFORNIA TO CAUSE
>CANCER AND BIRTH DEFECTS OR OTHER REPRODUCTIVE HARM.
>WASH HANDS AFTER USING
>
>Took the unit back and bought a similar vac form
>Hoover.... but had the SAME warning in the manual!
>
>What gives? Why would they market/sell a unit with
>such a toxic chemical in it?

Perhaps in the solder used in the electrical connections?

Just wash your hands and don't worry about it too much.

Dennis (evil)
--
"There is a fine line between participation and mockery" - Wally

== 3 of 8 ==
Date: Tues, Jan 8 2008 12:44 pm
From: me@privacy.net


"Rod Speed" <rod.speed.aaa@gmail.com> wrote:

>> Why would they market/sell a unit with such a toxic chemical in it?
>
>They dont, lead isnt a toxic chemical in that sense.

How so Rod?

If I'm handing the cord and get it on my hands.... am I
not exposing myself to some risk?

== 4 of 8 ==
Date: Tues, Jan 8 2008 12:44 pm
From: me@privacy.net


Dennis <dgw80@hotmail.com> wrote:

>>What gives? Why would they market/sell a unit with
>>such a toxic chemical in it?
>
>Perhaps in the solder used in the electrical connections?

Possible I suppose

== 5 of 8 ==
Date: Tues, Jan 8 2008 1:42 pm
From: "Rod Speed"


me@privacy.net wrote
> Rod Speed <rod.speed.aaa@gmail.com> wrote

>>> Why would they market/sell a unit with such a toxic chemical in it?

>> They dont, lead isnt a toxic chemical in that sense.

> How so Rod?

> If I'm handing the cord and get it on my hands....
> am I not exposing myself to some risk?

Nope, its been used in solder and other stuff like sinkers and shot for centurys.


== 6 of 8 ==
Date: Tues, Jan 8 2008 2:04 pm
From: Anthony Matonak


me@privacy.net wrote:
> I recently bought a small Dirt Devil Dynamite vacuum.
> After reading the manual carefully I found this
> warning:
>
> WARNING: THE CORDS, WIRES AND/OR CABLES SUPPLIED WITH
> THlS PRODUCT CONTAINS CHEMICALS, INCLUDING LEAD OR LEAD
> COMPOUNDS, KNOWN TO THE STATE OF CALIFORNIA TO CAUSE
> CANCER AND BIRTH DEFECTS OR OTHER REPRODUCTIVE HARM.
> WASH HANDS AFTER USING
>
> Took the unit back and bought a similar vac form
> Hoover.... but had the SAME warning in the manual!
>
> What gives? Why would they market/sell a unit with
> such a toxic chemical in it?

I did a quick google search and it appears that lead is
used to stabilize the PVC (Polyvinyl Chloride) plastic
that the cord is made from. Lead doesn't have to be used
but it's cheaper than less toxic materials so it'll be
found in almost all PVC.

These cords, and anything else with PVC like garden
hoses, have always had lead but it's only recently that
laws have been passed saying that they have to tell you
about it.

You might call the manufacturer and see if they can ship
you lead free cords. Some articles mentioned that as a
possibility.

Anthony

== 7 of 8 ==
Date: Tues, Jan 8 2008 2:24 pm
From: Al Bundy


m...@privacy.net wrote:
> I recently bought a small Dirt Devil Dynamite vacuum.
> After reading the manual carefully I found this
> warning:
>
> WARNING: THE CORDS, WIRES AND/OR CABLES SUPPLIED WITH
> THlS PRODUCT CONTAINS CHEMICALS, INCLUDING LEAD OR LEAD
> COMPOUNDS, KNOWN TO THE STATE OF CALIFORNIA TO CAUSE
> CANCER AND BIRTH DEFECTS OR OTHER REPRODUCTIVE HARM.
> WASH HANDS AFTER USING
>
> Took the unit back and bought a similar vac form
> Hoover.... but had the SAME warning in the manual!
>
> What gives? Why would they market/sell a unit with
> such a toxic chemical in it?

There is lead in some of the wiring connections and several places in
the motor itself. The amount is small and you are never in contact
with it.
Be more afraid of the dust you are taking into your lungs while using
any vacuum. What are you doing about that? Nothing, I bet.

== 8 of 8 ==
Date: Tues, Jan 8 2008 3:22 pm
From: hchickpea@hotmail.com


On Tue, 08 Jan 2008 13:59:01 -0600, me@privacy.net wrote:

>I recently bought a small Dirt Devil Dynamite vacuum.
>After reading the manual carefully I found this
>warning:
>
>WARNING: THE CORDS, WIRES AND/OR CABLES SUPPLIED WITH
>THlS PRODUCT CONTAINS CHEMICALS, INCLUDING LEAD OR LEAD
>COMPOUNDS, KNOWN TO THE STATE OF CALIFORNIA TO CAUSE
>CANCER AND BIRTH DEFECTS OR OTHER REPRODUCTIVE HARM.
>WASH HANDS AFTER USING
>
>Took the unit back and bought a similar vac form
>Hoover.... but had the SAME warning in the manual!
>
>What gives? Why would they market/sell a unit with
>such a toxic chemical in it?

First, the statement presumes that the STATE OF CALIFORNIA has somehow
become sentient. I sincerely doubt that has occured. Secondly, it
assumes that the STATE OF CALIFORNIA is somehow able to predict your
future health issues, which it cannot. Thirdly, it assumes that
people take STATE OF CALIFORNIA as an authority. I do not.

The STATE OF CALIFORNIA can sit on it and spin. I lived through the
era of lead in gasoline, have at least 300 pounds of lead in various
forms (mostly batteries) in various equipment and locations, have
soldered water pipes with lead solder, have cast lead, have reloaded
cartridges, and used lead weights while diving. A little lead solder
or lead in PVC in a rarely used appliance ain't goina kill me or
anyone else.

Why would someone market a product with such a toxic chemical?
Hopefully to piss off the nanny government in the STATE OF CALIFORNIA.


==============================================================================
TOPIC: Looking Forward
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/78cb5b0089fdc03b?hl=en
==============================================================================

== 1 of 1 ==
Date: Tues, Jan 8 2008 12:41 pm
From: pc


Chloe wrote:
> "Dawn" <linny4@hotmail.com> wrote in message
> news:vt72o3566eq2032ed8dd2tsnupbhh14jjb@4ax.com...
>> Hello to the group,
>> I wish to thank all the members here for all the ideas and help you
>> have given me since 1996. You have definitely added greatly to my
>> life. You have saved me lots of money and given me lots of laughs.
>>
>> This year I want to continue on my frugal journey.
>> I plan to finish funding my emergency fund, and
>> am already looking at seed catalogs for my garden this year.
>> I don't have any big vacation plans this year although we are going to
>> Vegas in a couple of weeks. Doing that on FF miles and hotel points.
>> Only expense will be food and entertainment.
>> Trying to keep the fire burning so I don't give my money to the
>> electric company.
>> Anyone else like to share their plans for this year?
>> Dawn, who still likes her frugal mindset.
>
> At year-end I added up what I'd spent on "bargain" clothing on Ebay. Yes,
> those $20 designer sweaters *are* great buys, but I realized that by surfing
> the site daily and buying something occasionally, those occasions were
> coming a lot closer together than I realized. Yes, I know to stay out of
> stores as the No. 1 effective way to limit spending, but I didn't apply that
> same principle to pointing and clicking.
>
> DH and I have for a long time been in circumstances (and have the years of
> life experience) where we don't have to devise a strict annual budget--we
> have a pretty good feel for how to live within our means without one. But
> this was a lapse that sneaked up on me, especially since I only need nice
> work clothes for one day a week. So my main resolution is to limit my
> recreational shopping for clothes to thrift stores on half price day. Can't
> do much damage that way!

This upcoming year frugal planning includes:
-Changing to a frequent flyer credit card.
-Taking advantage of utility company rebates for insulation and duct repair.
-Taking advantage of state rebates for hurricane mitigation upgrades.
-Looking for cheaper home insurance.
-Landscaping my backyard to cut down on upkeep and make it look nicer.

..PC


==============================================================================
TOPIC: how to catch a clever mouse?
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/bc8fd4ec8439afb6?hl=en
==============================================================================

== 1 of 5 ==
Date: Tues, Jan 8 2008 12:44 pm
From: George Grapman


The last time I saw infestation I purchased some glue traps. A few
hours later I heard a rattling sound on the floor. A rat had been caught
and was dragging the trap around. Since he was large and alive I went to
get a 2 by 4 to hit him on the head and at least knock him out. I
returned to the living room to find an empty trap sitting near the wall.
I went out immediately and purchased a dozen of the large poison
bars. The guy at the hardware store said to leave them until there were
no signs of two weeks. The next morning to of the bars were gone and
several others had obviously been chewed on. I never saw another sign of
infestation. Of course, this option is not good if you have pets or
small children.

== 2 of 5 ==
Date: Tues, Jan 8 2008 12:48 pm
From: George Grapman


Dennis wrote:
> On Tue, 8 Jan 2008 07:18:25 -0500, "OhioGuy" <none@none.net> wrote:
>
>> Can anyone suggest a better alternative to traditional mousetraps?
>> Something that will catch a mouse that seems smart and careful enough to
>> outwit a traditional trap?
>
> Here is a different idea: I have a leftover piece of sheet vinyl
> flooring stored in my workshop/barn (I'm sure I'll find a use for it
> someday :-). In the meantime, it is rolled into a tube-shape about
> 2.5 ft. tall and stored standing upright on its end in a corner.
>
> Every time I move the tube of flooring (usually rearranging junk or
> looking for something else), I find at least one, sometime more, dead
> dessicated mice at the bottom of the tube. Apparently, there is
> something about it that is irresistable to curious mice.
>
> Dennis (evil)
Reminds me of an accidental trapping. The plastic towel bar in the
bathroom kept coming out of its holder. One morning it was on the floor
and a a mouse was trapped inside. It was only open on one end so a took
a shopping bag, emptied the mouse into the bag, walked outside to the
storm drain on the corner and deposited the rodent.

== 3 of 5 ==
Date: Tues, Jan 8 2008 1:44 pm
From: "Rod Speed"


George Grapman <sfgeorge@paccbell.net> wrote:
> The last time I saw infestation I purchased some glue traps. A few
> hours later I heard a rattling sound on the floor. A rat had been
> caught and was dragging the trap around. Since he was large and alive
> I went to get a 2 by 4 to hit him on the head and at least knock him
> out. I returned to the living room to find an empty trap sitting near
> the wall. I went out immediately and purchased a dozen of the large
> poison bars. The guy at the hardware store said to leave them until there
> were no signs of two weeks. The next morning to of the bars were gone
> and several others had obviously been chewed on. I never saw another
> sign of infestation.

> Of course, this option is not good if you have pets or small children.

Its easy enough to put it where its out of the reach of either of those.


== 4 of 5 ==
Date: Tues, Jan 8 2008 4:18 pm
From: Melinda Meahan - take out TRASH to reply


Rod Speed wrote:
>
>> Of course, this option is not good if you have pets or small children.
>
> Its easy enough to put it where its out of the reach of either of those.

True, but if your cat or small dog catches one before it dies and
consumes it, your cat automatically gets a dose that could be toxic to
the pet.

--
Every job is a self-portrait of the person who does it. Autograph your
work with excellence.

== 5 of 5 ==
Date: Tues, Jan 8 2008 4:55 pm
From: "Rod Speed"


Melinda Meahan - take out TRASH to reply <mmeahan@TRASHsonic.net> wrote
> Rod Speed wrote

>>> Of course, this option is not good if you have pets or small children.

>> Its easy enough to put it where its out of the reach of either of those.

> True, but if your cat or small dog catches one before it dies and consumes it, your cat automatically gets a dose that
> could be toxic to the pet.

Unlikely, because the mouse is much smaller than a cat or dog.



==============================================================================
TOPIC: Chinese Exports Safe
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/656ddf21b6fa6b07?hl=en
==============================================================================

== 1 of 1 ==
Date: Tues, Jan 8 2008 1:12 pm
From: "Chloe"


<friesian@zoocrewphoto.com> wrote in message
news:2ace0655-e603-4738-b72b-61e721d6bfba@c4g2000hsg.googlegroups.com...
> On Jan 7, 6:02 am, "Chloe" <justsa...@spam.com> wrote:
>> <fries...@zoocrewphoto.com> wrote in message
>>
>> news:30351a97-8510-4141-b281-74f4b9f015f3@i12g2000prf.googlegroups.com...>
>> On Jan 6, 1:42 pm, Bernardo Gui <waile2...@mypacks.net> wrote:
>> > After the pet food problems, the good cat food companies started
>> > sending samples of their products to the cat shows. Everybody went
>> > home with a variety of samples. I was able to test a variety of US
>> > made, grain-free cat foods. A lot of people opted to spend more money
>> > on expensive cat foods and never go back to the cheaper crap that may
>> > end up with new problems in the future.
>>
>> <snip>
>>
>> Can you recommend some brands? The pet food problem was especially
>> troubling
>> because it was (and still is) so difficult to know how to avoid the
>> Chinese
>> ingredients. OTOH, I hate spending money on food the cats don't like the
>> taste of.
>
>
> Innova is a great brand. Their evo version has no grains at all, but
> both versions are safe as they do not use hinese suppliers.
>
> Royal Canin is good too. They did have have two items that were
> recalled, but they immediately quit using ingredients from China.
>
> Those are the two brands of dry food that I use.
>
> Other good dry foods are:
>
> Natural Balance
> Eagle Pack
> Chicken Soup for the Cat Lover's Soul
> Diamond
> Precise
> California something
>
> There are more, but I don't have all of the samples still. If you have
> any local cat shows, you can go and see what samples they have there
> for free. Send me an email offlist, and I can help you find some cat
> shows. (friesian@zoocrewphoto.com)
>
> As for wet food, any of the above brands. And a bunch more. My cats
> are really picky and only like Fancy Feast (none of which were
> recalled). To be safe, check the ingredients list for wheat gluten.
> Usually, the canned foods with sliced meats or gravy will have the
> weat gluten.
>
> Also, check out your area for a specialty pet store. The big stores
> like Petco and Petsmart will carry some of these brands. But not as
> many. The specialty stores are more like a health store. They tend to
> skip the crappy brands and go with the good brands.
>
> Some of these companies will also allow you to buy them in larger bags
> via mail and get a better price on them. Or, if you can buy them at a
> cat show, they reps will usually have a discount on them.

Thanks, I know where and when the cat show is! Appreciate all the advice. My
cats are big into Fancy Feast, too. I may just stick with that, but I'll
keep an eye out for some of the others.
>



==============================================================================
TOPIC: Best frugal technology deal you've gotten
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/432b1da46fece658?hl=en
==============================================================================

== 1 of 4 ==
Date: Tues, Jan 8 2008 1:46 pm
From: Anthony Matonak


pc wrote:
...
> The only thing that I wish I could find is a cheap way to connect a
> pcmcia Verizon card to USB. Any ideas out there?

What does the Verizon card do? Wireless internet? Can't you find
a USB device that does the same thing? Something like this...
http://www.1800mobiles.com/verizon-novatel-s720-broadband.html

Anthony

== 2 of 4 ==
Date: Tues, Jan 8 2008 2:01 pm
From: Seerialmom


On Jan 8, 10:50 am, "Rod Speed" <rod.speed....@gmail.com> wrote:
> Seerialmom <seerial...@yahoo.com> wrote:
> > On Jan 7, 6:30 pm, "Rod Speed" <rod.speed....@gmail.com> wrote:
> >> Seerialmom <seerial...@yahoo.com> wrote:
> >>> On Jan 7, 2:02 pm, pc <p...@somewhere.com> wrote:
> >>>> Gordon wrote:
> >>>>> "OhioGuy" <n...@none.net> wrote innews:fllcpc$f0h$1@aioe.org:
>
> >>>>>> What's the best technology deal you've gotten in the past couple
> >>>>>> of months?
>
> >>>>>> For me, it was the PNY 2 GB USB flash drive I picked up at
> >>>>>> Staples for
> >>>>>> $8.48 using a competitor's $15 off coupon. I actually got two of
> >>>>>> them, to replace the old 512 MB ones my wife and I were using.
>
> >>>>> Free iPod from Key Bank.
>
> >>>> My best frugal technology purchase [not 'deal'..because I paid the
> >>>> going rate] was an Asus eeepc that I got for Christmas.
>
> >>>> My old laptop was on it's last legs so I went for the eeepc. I am
> >>>> in love with this thing. And I am finally taking the Linux leap.
> >>>> The only thing that I wish I could find is a cheap way to
> >>>> connect a pcmcia Verizon card to USB. Any ideas out there?
> >>> Isn't there a PCMCIA to USB adapter?
>
> >> Yes, but it wont do what he wants to do.
>
> >>> I'm pretty sure I saw one recently...check on frys.com
> > You mean connect the PCMCIA to USB "cheaply"?
>
> Nope, he doesnt want to connect PCMCIA to USB, he wants to
> connect a pcmcia Verizon card to USB, a different matter entirely.- Hide quoted text -
>
> - Show quoted text -

Why is it different? He's got a Verizon PCMCIA "notebook" card and he
needs an adapter that will allow connection/use on a desktop (USB port
for example).

== 3 of 4 ==
Date: Tues, Jan 8 2008 4:00 pm
From: The Real Bev


Linux and linux applications. Moreover we got $100 off on a demo Acer
notebook because the store couldn't get it to boot Vista, yielding a
$100 profit!

--
Cheers, Bev
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
The early bird gets the worm, the second mouse gets the cheese.

== 4 of 4 ==
Date: Tues, Jan 8 2008 4:58 pm
From: "Rod Speed"


Seerialmom <seerialmom@yahoo.com> wrote:
> On Jan 8, 10:50 am, "Rod Speed" <rod.speed....@gmail.com> wrote:
>> Seerialmom <seerial...@yahoo.com> wrote:
>>> On Jan 7, 6:30 pm, "Rod Speed" <rod.speed....@gmail.com> wrote:
>>>> Seerialmom <seerial...@yahoo.com> wrote:
>>>>> On Jan 7, 2:02 pm, pc <p...@somewhere.com> wrote:
>>>>>> Gordon wrote:
>>>>>>> "OhioGuy" <n...@none.net> wrote innews:fllcpc$f0h$1@aioe.org:
>>
>>>>>>>> What's the best technology deal you've gotten in the past
>>>>>>>> couple of months?
>>
>>>>>>>> For me, it was the PNY 2 GB USB flash drive I picked up at
>>>>>>>> Staples for
>>>>>>>> $8.48 using a competitor's $15 off coupon. I actually got two
>>>>>>>> of them, to replace the old 512 MB ones my wife and I were
>>>>>>>> using.
>>
>>>>>>> Free iPod from Key Bank.
>>
>>>>>> My best frugal technology purchase [not 'deal'..because I paid
>>>>>> the going rate] was an Asus eeepc that I got for Christmas.
>>
>>>>>> My old laptop was on it's last legs so I went for the eeepc. I am
>>>>>> in love with this thing. And I am finally taking the Linux leap.
>>>>>> The only thing that I wish I could find is a cheap way to
>>>>>> connect a pcmcia Verizon card to USB. Any ideas out there?

>>>>> Isn't there a PCMCIA to USB adapter?
>>
>>>> Yes, but it wont do what he wants to do.
>>
>>>>> I'm pretty sure I saw one recently...check on frys.com
>>> You mean connect the PCMCIA to USB "cheaply"?
>>
>> Nope, he doesnt want to connect PCMCIA to USB, he wants to
>> connect a pcmcia Verizon card to USB, a different matter entirely.-

> Why is it different?

Because the technology is completely different. A PCMCIA card that provides
a USB port is nothing like what is needed to run a PCMCIA card off a USB port.

> He's got a Verizon PCMCIA "notebook" card and he needs an adapter
> that will allow connection/use on a desktop (USB port for example).

Yes, and what you were talking about wont work in that situation.

There wont even be anywhere to plug the PCMCIA cards if the desktop doesnt have card ports.



==============================================================================
TOPIC: Experimental Drugs. Your Moral Compass?
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/b3c607adfe84a43e?hl=en
==============================================================================

== 1 of 1 ==
Date: Tues, Jan 8 2008 3:11 pm
From: PaPaPeng

Here's a good one for you to think about. Its this a good thing, a
benign thing or something evil and so like China to put people's lives
at stake?


Experimental drugs flourish in China
January 9, 2008
http://www.atimes.com/atimes/China_Business/JA09Cb02.html

BROOKLIN, Ontario, Canada - China's booming medical biotechnology
industry is producing controversial drugs and gene therapy treatment
programs that are being sought out by critically ill foreigners
seeking potential cures unavailable elsewhere.

China's Beike Biotechnologies harvests stem cells from the umbilical
cord or amniotic membrane and injects them into patient's spinal
region. More than 1,000 patients, including 60 foreigners, have been
treated for a variety of conditions including Alzheimer's disease,
autism, brain trauma, cerebral palsy and spinal cord injury, according
to a study published Monday in the journal Nature Biotechnology.

"We met foreigners there who were happy with Beike's treatments," said
Peter Singer of the McLaughlin-Rotman Center for Global Health at the
University of Toronto and co-author of the study.

However, China's regulatory agency, the State Food and Drug
Administration (SFDA), did not require clinical trials, making it
difficult to evaluate the efficacy of these therapies, Singer said. It
is a controversial approach and Beike and others in China would be
considered "rogue companies" in North America or Europe, he said.

Although less than 10 years old, China's medical biotech industry has
become both an innovator and a place where the world's biggest
pharmaceutical companies contract out their very expensive clinical
research and trials. One of China's largest firms, WuXi PharmaTech, is
listed on the New York Stock Exchange and recently acquired a US
biologics firm.

"The Chinese biotechnology industry is like a baby dragon, which will
grow quickly and soon become hard to ignore," Singer said.

In 2007, China had sales of US$3 billion in biopharmaceuticals,
dwarfed by the $59 billion in sales by US biotechnology companies in
2006, according to the accounting firm Ernst & Young LLP.

Singer and colleagues interviewed 22 Chinese companies to obtain the
first detailed analysis of developments in the rapidly growing but
largely unknown health biotech sector.

Spurred by government investment, China developed the world's first
commercialized gene therapy product called Gendicine. It is used in
the treatment of head and neck cancers and more than 5,000 patients
have been treated so far, about 400 of them from overseas. The drug is
currently undergoing further clinical trials in China for several new
indications, including liver, abdominal and pancreatic cancer.

Chinese firms are also developing vaccines to address both local and
global needs. They include Shanghai United Cell Biotech, which is
manufacturing and marketing one of only two oral cholera vaccines
available worldwide (and the only one available in tablet form). Other
firms are working on an oral HIV vaccine and novel vaccines against
Japanese Encephalitis, SARS and pandemic avian influenza (H5N1
strain).

However, China's primary focus is on meeting the health needs of its
1.3 billion inhabitants.

"China is not just a low-cost manufacturer. It is investing in drug
research and development," said co-author Sarah Frew, a research
associate at the McLaughlin Rotman Center for Global Health. "There
are many innovative products either on the market or close to being
marketed."

Shanghai's Sunway Biotech Company has developed a gene therapy
treatment for cancer called H101, which is licensed by Onyx
Pharmaceuticals Inc of California. Sunway did all of the clinical
development and trials and brought the product to market far faster
and less expensively than Onyx could have, she said.

Experts note that China is the world leader in gene therapy simply
because US and European companies have much tougher safety and
efficacy requirements.

Gene therapies use genetically engineered viruses to transport genetic
material into the nucleus of cells that are malfunctioning. No such
therapy has been approved by US regulators as safe and effective.
Human testing has been temporarily stopped several times in the US and
Europe because of patient deaths.

"Regulations to protect patients in China are considerably weaker than
in the US," said Peter Laurie, deputy director of Public Citizen's
health research group, a Washington-based non-profit watchdog group.

A few years ago, US researchers working in China deliberately infected
Chinese AIDS patients with malaria in hopes the resulting malarial
fever would destroy the AIDS virus. Such experiments are illegal in
the US, and widely considered dangerous and unethical, Laurie said.

"Any foreign company doing clinical trials or clinical research in
China is ethically suspect unless it's doing so to improve the health
of people there," he said.

International standards for drug testing are rigorous, time-consuming
and expensive, but they are crucial to protect patients, he added.

Frew says China's drug safety regulator, the SFDA, is modeled on the
US Food and Drug Administration. "The standards are quite high but
enforcement has been tainted by corruption," she said.

Last July, Zheng Xiaoyu, the head of the SFDA, was executed for taking
bribes from companies to approve their products, including an
antibiotic that killed several people. Since that scandal, the SFDA
has been much stricter and more serious about rebuilding its
credibility, said Frew.

However, China's researchers do not always follow international
standards and are unlikely to be able to export their products or
therapies to the developed world in the near future. That's one reason
why China's medical biotech hasn't grown faster.

The study notes that international investors see enormous potential in
the sector to become the world's pharmacy for generic drugs and the
next generation of drug and treatment blockbusters. But there has been
little outside investment thanks to poorly enforced regulations and
China's uncertain financial system, rigid restrictions on the export
of capital and continuing doubts about the Chinese government's
protection of intellectual property rights.

"China still has one foot in the closed society of the past," said
Singer. "For the sake of both national and global health, we hope
China will embrace the financial and regulatory reforms needed to
attract the venture capital required for sustained innovation in the
health biotech sector."

(Inter Press Service)


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==============================================================================
TOPIC: Donation Question
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/ede7dc79ef5b9e1e?hl=en
==============================================================================

== 1 of 1 ==
Date: Tues, Jan 8 2008 3:43 pm
From: The Real Bev


Evelyn C. Leeper wrote:

> The Real Bev wrote:
>> Evelyn C. Leeper wrote:
>>> Joe wrote:
>>>> Bev wrote:
>>>>> I suspect that if they're going to quibble about the glue that they
>>>>> should then replace those stamps with usable ones.
>>>>
>>>> Funny. Our local guy and local postmaster dude also bounced back a
>>>> few... I simply figured it wasn't worth the hassle... So I proceeded
>>>> to soak them in warm water, laid them out to dry and glue sticked
>>>> them to the next letter so they couldn't tell. Not frugal use of my
>>>> time, but I felt better.
>>>
>>> Why don't people just take the envelope, put a large address label
>>> over the charity's address, and write the new address on that?
>>
>> Some of them have barcodes printed on the bottom, and the envelopes are
>> generally too small. Besides, then you have to buy the address labels.
>
> White-Out over the bar codes works fine (or wide black marker pen).
>
> And I suspect an envelope costs more than a label (though I haven't
> checked). I use plain white labels that I also use for labeling boxes, etc.

I bought a box of 1000 business envelopes for a buck at a yard sale
several years ago. No matter how many I use, the box is still full :-)

--
Cheers, Bev
================================================================
"Is there any way I can help without actually getting involved?"
-- Jennifer, WKRP


==============================================================================
TOPIC: Web 2.0-Whats The Next Big Thing? See What Yahoo Said !
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/e6966aae817e94d9?hl=en
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== 1 of 1 ==
Date: Tues, Jan 8 2008 4:40 pm
From: Paidsocial


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TOPIC: Tips on living cheaply in the Philadelphia region
http://groups.google.com/group/misc.consumers.frugal-living/browse_thread/thread/7c4d094a72698045?hl=en
==============================================================================

== 1 of 1 ==
Date: Tues, Jan 8 2008 4:53 pm
From: Joe


http://home.comcast.net/~plutarch/frugal-philly.html

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