Frugal Living: Mar 22, 2010

Monday, March 22, 2010

misc.consumers.frugal-living - 11 new messages in 10 topics - digest

misc.consumers.frugal-living
http://groups.google.com/group/misc.consumers.frugal-living?hl=en

misc.consumers.frugal-living@googlegroups.com

Today's topics:

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TOPIC: Are Charity and Welfare wrong?
http://groups.google.com/group/misc.consumers.frugal-living/t/55618dc9d4117e75?hl=en
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== 1 of 2 ==
Date: Sat, Mar 20 2010 8:07 pm
From: "TibetanMonkey, Originator of the Banana Kung-Fu"

On Mar 20, 9:41 pm, Doris Briscoe <dbrisc...@gmail.com> wrote:
> I know about walking I have done alot in my life time. dj

I've even tried race walking, so I love it. But beyond 5 miles can get
kind of boring. That's why I wanted to ride a bike around, and I do
have the bikes, but I'm not riding bike on sidewalks. Too much
stress.

So the easy path is just to be in the cage. Cozy cage I got though.

== 2 of 2 ==
Date: Sun, Mar 21 2010 9:37 am
From: "TibetanMonkey, Originator of the Banana Kung-Fu"

People at a local forum seem surprised that I try to solve mundane
problems by attacking religion. Is religion rendering democracy
another fairy tale?

"Tibetan Monkey, please PM me when you see this as I need to
understand why your posting like this? It's rather confusing for new
members and mentioning Religion in several posts and references to
race and nationality might actually offend some."

***

Then I reply:

These debates are often coming from Atheism vs. Religion groups, where
I make the point that the indifference of the "sheep" makes all this
"jungle" possible. We are supposed to live in democracy where there's
debate, but when people look the other way, I crank up the heat to
make them react.

It may look like Religion and Democracy are fairy tales. ;)

---------------------------------------------------------------------------

THE WISE TIBETAN MONKEY SAYS

"See the truth, hear the truth, speak the truth"

http://webspawner.com/users/BANANAREVOLUTION

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TOPIC: DISCUSSION FOR THE DEVELOPMENT OF CURRICULAM
http://groups.google.com/group/misc.consumers.frugal-living/t/d034beaad7692faa?hl=en
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== 1 of 1 ==
Date: Sun, Mar 21 2010 4:58 am
From: MMM <2ennel.0569@gmail.com>

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TOPIC: PAYING TOO MUCH FOR DRUGS? It's Because Big Pharma Can Afford To Pay
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http://groups.google.com/group/misc.consumers.frugal-living/t/cb6f027e06be4ce3?hl=en
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== 1 of 1 ==
Date: Sun, Mar 21 2010 8:21 am
From: perriegh

" 'It's an unbearable cost to a system that's going broke. We can't
even afford to pay for effective,
safe therapies.' "
-- Jerry Avorn, a professor at Harvard Medical
School.

"Pharmaceutical companies spend about $1 billion to develop and test a
new drug. To recoup their investment, the companies want doctors to
prescribe their drugs as widely as possible."

Funny, but you tea-party twits never seem to mention the main cause of
runaway, break-the-bank medical costs.

===================
"When drug makers' profits outweigh penalties"

By David Evans
Bloomberg News
Sunday, March 21, 2010; G01

PROSECUTER Michael Loucks remembers clearly when attorneys for Pfizer,
the world's largest drug company, looked across the table and promised
it wouldn't break the law again. ¶ It was January 2004, and the
lawyers were negotiating in a conference room on the ninth floor of
the federal courthouse in Boston, where Loucks was head of the health-
care fraud unit of the U.S. Attorney's Office. One of Pfizer's units
had been pushing doctors to prescribe an epilepsy drug called
Neurontin for uses the Food and Drug Administration had never
approved. ¶ In the agreement the lawyers eventually hammered out, the
Pfizer unit, Warner-Lambert, pleaded guilty to two felony counts of
marketing a drug for unapproved uses. New York-based Pfizer agreed to
pay $430 million in criminal fines and civil penalties, and the
company's lawyers assured Loucks and three other prosecutors that
Pfizer and its units would stop promoting drugs for unauthorized
purposes. ¶ What Loucks, who was acting U.S. attorney in Boston until
November, didn't know until years later was that Pfizer managers were
breaking that pledge not to practice off-label marketing even before
the ink was dry on their plea.

On the morning of Sept. 2, 2009, another Pfizer unit, Pharmacia &
Upjohn, agreed to plead guilty to the same crime. This time, Pfizer
executives had been instructing more than 100 salespeople to promote
Bextra -- a drug approved only for the relief of arthritis and
menstrual discomfort -- for treatment of acute pain of all kinds.

For this new felony, Pfizer paid the largest criminal fine in U.S.
history: $1.19 billion. On the same day, it paid $1 billion to settle
civil cases involving the off-label promotion of Bextra and three
other drugs with the United States and 49 states.

"At the very same time Pfizer was in our office negotiating and
resolving the allegations of criminal conduct in 2004, Pfizer was
itself in its other operations violating those very same laws,"
Loucks, 54, says. "They've repeatedly marketed drugs for things they
knew they couldn't demonstrate efficacy for. That's clearly criminal."

The penalties Pfizer paid for promoting Bextra off-label were the
latest chapter in the drug's benighted history. The FDA found Bextra
to be so dangerous that Pfizer took it off the market for all uses in
2005.

Across the United States, pharmaceutical companies have pleaded guilty
to criminal charges or paid penalties in civil cases when the Justice
Department finds that they deceptively marketed drugs for unapproved
uses, putting millions of people at risk of chest infections, heart
attacks, suicidal impulses or death.

It used to be legal for companies to promote drugs in the United
States for any use. Congress banned the practice in 1962, requiring
pharmaceutical companies to first prove their drugs were safe and
effective for specific uses.

If the law is clear, why do drug companies keep breaking it? The
answer lies in economics. Pharmaceutical companies spend about $1
billion to develop and test a new drug. To recoup their investment,
the companies want doctors to prescribe their drugs as widely as
possible.

Since May 2004, Pfizer, Eli Lilly, Bristol-Myers Squibb and four other
drug companies have paid a total of $7 billion in fines and penalties.
Six of the companies admitted in court that they marketed medicines
for unapproved uses. In September 2007, New York-based Bristol-Myers
paid $515 million -- without admitting or denying wrongdoing -- to
federal and state governments in a civil lawsuit brought by the
Justice Department. The six other companies pleaded guilty in criminal
cases.

In January 2009, Indianapolis-based Lilly, the largest U.S.
psychiatric drugmaker, pleaded guilty and paid $1.42 billion in fines
and penalties to settle charges that it had for at least four years
illegally marketed Zyprexa, a drug approved for the treatment of
schizophrenia, as a remedy for dementia in elderly patients.

In five company-sponsored clinical trials, 31 people out of 1,184
participants died after taking the drug for dementia -- twice the
death rate for those taking a placebo, according to an article in the
Journal of the American Medical Association.

"Marketing departments of many drug companies don't respect any
boundaries of professionalism or the law," says Jerry Avorn, a
professor at Harvard Medical School. "The Pfizer and Lilly cases
involved the illegal promotion of drugs that have been shown to cause
substantial harm and death to patients."

The widespread off-label promotion of drugs is yet another
manifestation of a health-care system that has become dysfunctional.

"It's an unbearable cost to a system that's going broke," Avorn says.
"We can't even afford to pay for effective, safe therapies."

About 15 percent of all U.S. drug sales are for unapproved uses
without adequate evidence the medicines work, according to a study by
Randall Stafford, a medical professor at Stanford University.

As large as the penalties are for drug companies caught breaking the
off-label law, the fines are tiny compared with the firms' annual
revenue.

The $2.3 billion in fines and penalties Pfizer paid for marketing
Bextra and three other drugs cited in the Sept. 2 plea agreement for
off-label uses amount to just 14 percent of its $16.8 billion in
revenue from selling those medicines from 2001 to 2008.

The total of $2.75 billion Pfizer has paid in off-label penalties
since 2004 is a little more than 1 percent of the company's revenue of
$245 billion from 2004 to 2008.

Lilly already had a criminal conviction for misbranding a drug when it
broke the law again in promoting schizophrenia drug Zyprexa for off-
label uses beginning in 1999. The medication provided Lilly with $36
billion in revenue from 2000 to 2008. That's more than 25 times as
much as the total penalties Lilly paid in January.

Companies regard the risk of multimillion-dollar penalties as just
another cost of doing business, says Lon Schneider, a professor at the
University of Southern California's Keck School of Medicine in Los
Angeles. In 2006, he led a study for the National Institute of Mental
Health of off-label use of drugs, including Zyprexa.

"There's an unwritten business plan," he says. "They're drivers that
knowingly speed. If stopped, they pay the fine, and then they do it
again."
Paying the doctors

In pushing off-label use of drugs, companies find ready and willing
partners in physicians. Under the fragmented system of U.S. medical
regulation, it's legal for doctors to prescribe FDA-approved drugs for
any use. The FDA has no authority over doctors, only over drug
companies, regarding off-label practices. It's up to the states to
oversee physicians.

"I think the physician community has to take some ownership
responsibility and do their own due diligence beyond the sales and
marketing person," says Boston's former U.S. Attorney Michael
Sullivan.

Doctors generally don't tell people they're prescribing drugs pitched
to them by pharmaceutical salespeople for unapproved treatments, says
Peter Lurie, former deputy medical director of Public Citizen, a
Washington-based public interest group. Most doctors don't keep track
of FDA-approved uses of drugs, he says.

"The great majority of doctors have no idea; they don't even
understand the distinction between on- and off-labeling," he says.

Pfizer's marketing program offered doctors up to $1,000 a day to allow
a Pfizer salesperson to spend time with the physician and his
patients, according to a whistle-blower lawsuit filed by John
Kopchinski, who worked as a salesman at Pfizer from 1992 to 2003.

"By 'pairing up' with a physician, the sales representative was able
to promote over a period of many hours, without the usual problems of
gaining access to prescribing physicians," Kopchinski says. "In
essence, this amounted to Pfizer buying access to physicians."

Pfizer spokesman Chris Loder says the company stopped what it calls
"mentorships" in 2005. He says Pfizer paid doctors $250 a visit. The
goal was clear: Get doctors to prescribe a new drug as widely as
possible.

Pfizer's Neurontin is a case in point. The FDA approved the drug as a
supplemental medication to treat epilepsy in 1993. Pfizer took in
$2.27 billion from sales of Neurontin in 2002. A full 94 percent --
$2.12 billion -- of that revenue came from off-label use, according to
the prosecutors' 2004 Pfizer sentencing memo.

Since 2004, companies that are now Pfizer divisions have pleaded
guilty to off-label marketing of two drugs. Pfizer continued off-label
promotions for these medications after buying the firms, according to
documents.

Pfizer first stepped into an off-label scheme in 1999, when it offered
to buy Warner-Lambert, based in New Jersey. Prosecutors charged that
Warner-Lambert marketed Neurontin off-label between 1995 and 1999.

Warner-Lambert admitted doing so for one year in a May 2004 guilty
plea for which Pfizer paid $430 million in fines and penalties.

When the FDA approved Neurontin in 1993 to be used only along with
other epilepsy drugs, the agency wrote that as a side effect, the drug
can induce depression and suicidal thoughts in patients.
The whistle-blower

Much of what prosecutors learned about Warner-Lambert's marketing of
Neurontin comes from a former employee, David Franklin, who holds a
Ph.D. in microbiology.

Franklin, 48, whose title at Warner-Lambert was medical liaison, says
his job involved more salesmanship than science. He told doctors that
Neurontin was the best drug for a dozen off-label uses, including pain
relief, bipolar disease and depression.

"Technically, I had responsibility for answering physician questions
about all of Parke-Davis's drugs," Franklin says. "In practice, my
real job was to promote Neurontin for off-label indications heavily --
to the exclusion of just about everything else."

Franklin says he knew such uses of the drug had no scientific support
for effectiveness and safety.

"I was actually undermining their ability to fulfill the Hippocratic
oath," Franklin says, referring to a physician's pledge to "First, do
no harm."

After working for Warner-Lambert for three months, Franklin quit and
filed a whistle-blower lawsuit on behalf of taxpayers to recover money
the government paid for illegally promoted drugs. He stood to collect
as much as 30 percent of any settlement the company made with the
government.

Franklin had to wait four years -- until 2000 -- before the Justice
Department began a criminal investigation. In November 1999, Pfizer
made its public offer to buy Warner-Lambert. In January 2000, a
federal grand jury in Boston issued subpoenas to Warner-Lambert
employees to testify about the marketing of Neurontin.

That March, Warner-Lambert's annual report disclosed that prosecutors
were building a criminal case. Undeterred, Pfizer bought Warner-
Lambert in June for $87 billion -- the third-largest merger in U.S.
history.
More sales than Viagra

A year after the acquisition, the FDA discovered that Neurontin was
still being marketed off-label. In a June, 2001 letter to the company,
the agency wrote that Pfizer's promotion of the drug "is misleading
and in violation of the Federal Food, Drug and Cosmetics Act."

Pfizer marketed Neurontin off-label after receiving that letter,
agency records show. For 2001, Pfizer reported revenue of $1.75
billion from Neurontin sales, making it the company's fourth-largest-
selling drug that year, ahead of impotence pill Viagra, which
Neurontin topped for four years.

As Neurontin sales soared to $2.27 billion in 2002, the FDA found that
Pfizer was improperly claiming that the drug was useful for a broader
range of brain disorders than scientific evidence had established.

The agency sent a letter dated July 1, 2002, that said the company's
marketing practices were in violation of FDA rules. It asked Pfizer to
stop using misleading promotions. Pfizer reported $2.7 billion in
revenue from Neurontin in 2003. Overall, the drug has provided Pfizer
with $12 billion in revenue.

Pfizer spokesman Chris Loder says, "Regarding the 2001 and 2002 FDA
letters, we do not believe that they were suggestive of any continuing
off-label promotion."

For blowing the whistle on his employer, Franklin collected $24.6
million under the False Claims Act.

Prosecutors Loucks and Sullivan got involved in the case after
Franklin filed his suit, relying on information from Franklin and
their own investigation. Before 2004, prosecutions for off-label
marketing were rare.

"Until a couple of these cases became public, companies were probably
saying, 'Everybody does it this way,' " Sullivan says.

Loucks had a track record in off-label prosecutions. In 1994, he
negotiated a $61 million settlement with C.R. Bard of New Jersey,
which pleaded guilty to promoting off-label use of a heart catheter
that led to patient deaths.
The off-label campaign

In the January 2004 settlement negotiations with Loucks, Sullivan and
two other prosecutors, Pfizer's lawyers assured the U.S. Attorney's
Office that the company wouldn't market drugs off-label.

"They asserted that the company understood the rules and had taken
steps to assure corporate compliance with the law," Loucks says. "We
remember those promises."

What Pfizer's lawyers didn't tell the prosecutors was that Pfizer was
at that moment running an off-label marketing promotion using more
than 100 salespeople who were pitching Bextra, according to a Pfizer
sales manager who pleaded guilty to misbranding a drug in March 2009.

Pharmacia & Upjohn developed Bextra, which was approved by the FDA in
2001 for only the treatment of arthritis and menstrual discomfort.

P&U and Pfizer had by then crafted a joint marketing agreement to sell
the drug. In November 2001, Mary Holloway, a Pfizer Northeast regional
manager, began illegally training and directing her sales team to
market Bextra for the relief of acute pain, Holloway admitted in the
plea.

On Dec. 4, 2001, Pfizer executives sent Holloway a copy of a nonpublic
FDA letter to the company. The agency had denied Pfizer's application
to market Bextra for acute pain. Clinical trials had shown Bextra
could cause heart damage and death.

Pfizer bought Pharmacia & Upjohn in April 2003. From 2001 through
2003, P&U, first as an independent company and then as a unit of
Pfizer, paid doctors more than $5 million in cash to lure them to
resorts, where salespeople illegally pitched off-label uses for
Bextra, P&U admitted.

In her guilty plea, Holloway said her team had solicited hospitals to
create protocols to buy Bextra for the unapproved purpose of acute
pain relief. Her representatives didn't mention the increased risk of
heart attacks in their marketing.

They told doctors that side effects were no worse than those of a
sugar pill, Holloway said.

In 2003, Holloway reported her unit's off-label promotions of Bextra
up the corporate ladder at Pfizer, according to a presentencing memo
to the judge written by Robert Ullmann, Holloway's attorney. Top
managers didn't attempt to halt the illegal conduct, the memo said.

By late 2004, Bextra reached blockbuster status, with annual sales of
$1.29 billion. Holloway promoted Bextra until the FDA asked Pfizer in
April 2005 to pull it from the market for all uses.

The agency concluded that the drug increased the risk of heart
attacks, chest infections and strokes in cardiac surgery patients. In
June 2009, Holloway, 47, was sentenced to two years on probation and
fined $75,000. She didn't return phone calls seeking comment.
'We regret . . . '

By 2007, the criminal and civil cases against Pfizer, its employees
and its subsidiaries had begun to mount. The tally of drugs cited by
federal prosecutors for off-label promotion reached six by 2009. In
April 2007, P&U pleaded guilty to a felony charge of offering a $12
million kickback to a pharmacy benefit manager. Pfizer paid a criminal
fine of $19.7 million. In September 2009, Pfizer agreed to pay $2.2
billion in fines and penalties. P&U pleaded guilty to a felony charge
of misbranding Bextra with the intent to defraud. After the
settlement, Pfizer general counsel Amy Schulman said the company had
learned its lesson.

"We regret certain actions we've taken in the past," she said.
"Corporate integrity is an absolute priority for Pfizer."

One reason drug companies keep breaking the law may be because
prosecutors and judges have been unwilling to use the ultimate
sanction -- a felony conviction that would exclude a company from
selling its drugs for reimbursement by state health programs and
federal Medicare.

At Pfizer's Pharmacia sentencing in October, U.S. District Court Judge
Douglas Woodlock said companies don't appear to take the law
seriously. "It has become something of a cost of doing business for
some of these corporations, to shed their skin like certain animals
and leave the skin and move on," he said.

As prosecutors continue to uncover patterns of deceit in off-label
marketing, millions of patients across the nation remain in the dark.
Doctors often choose the medications based on dishonest marketing by
drug company salesmen.

Loucks says that putting an end to the criminal off-label schemes will
be difficult. As drugmakers repeatedly plead guilty, they've shown
they're willing to pay hundreds of millions of dollars in fines as a
cost of generating billions in revenue.

The best hope, Loucks says, is that drug companies actually honor the
promises they keep making -- and keep breaking -- to obey the law of
the land.

As much as $100 million for health-care fraud enforcement is tied up
in the stalled reform legislation, according to Loucks.

"It will be increasingly hard for the threat of exclusion to seem
credible and thus serve as a deterrent to bad corporate behavior," he
says, "unless Congress supports health-care fraud prosecutions with
more money."

[A version of this story originally appeared in Bloomberg Markets
Magazine. It was awarded a 2010 Society of American Business Editors
and Writers award for enterprise reporting and general excellence.]

http://www.washingtonpost.com/wp-dyn/content/article/2010/03/19/AR2010031905578.html

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== 1 of 1 ==
Date: Sun, Mar 21 2010 11:49 am
From: SMS

On 19/03/10 12:18 PM, Ohioguy wrote:
> Previously, we lived in a city where water, sewer & trash were bundled
> together.
>
> At our new city, they are separate. According to our neighbor, trash
> pickup is $30 a month.
>
> I was curious - is this high, low, average, or what?
>
> I was tempted to call around and see if any private companies would
> service us. We have water, telephone, electric, etc., but nobody has
> contacted us about setting up trash pickup. I was wondering if we might
> be able to set something up with a larger container and just twice a
> month, or something like that.

That's about what we pay for trash, recycling, and yard waste bins, and
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I know in nearby San Jose there was a story of someone that didn't want
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up for garbage service, and that it was not optional.

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TOPIC: Ocean County New Jersey Attorney Novins Fights Online Abusers
http://groups.google.com/group/misc.consumers.frugal-living/t/ff4610c716b31e79?hl=en
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== 1 of 1 ==
Date: Sun, Mar 21 2010 7:34 pm
From: "atlas bugged"

Anonymous posters using falsified identifiers have e-mailed prominent
attorney Charles Novins with apologies, concerned they may be found out, and
jockeying to avoid being sued and exposed, as several others have.

The falsified and libelous posts, alleging "drug addiction," "rape" and
other ridiculous defamation appeared on Usenet and republished in various
internet fora.

Typical online apologies have appeared publicly, including:

http://apologee7.notlong.com
and
http://apologee8.notlong.com

The Novins firm has become a clearinghouse for victims of internet abuse,
and has been recognized as one of the first to fight back with success.
Asked what he advises people who seek his counsel, Novins said:

"Would-be bullies are the same everywhere and every-when, and it has ever
been thus. Ultimately, they're cowards, and the minute anyone stands up to
them, they scatter like insects.

They act as they do out of self-loathing and fear, but this can not and
should not earn them sympathy.

The miscreant's metaphorical bloody nose is just as beneficial to the abuser
as to the abused, and in no way does the chioice to fight back make the two
sides the same in any way."

Novins can be contacted at www.novins.com

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== 1 of 1 ==
Date: Sun, Mar 21 2010 10:09 pm
From: LLL <1ennel.0569@gmail.com>

http://123maza.com/75/expressions

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TOPIC: 今天，又想妳了！
http://groups.google.com/group/misc.consumers.frugal-living/t/92100d8f8156dbdc?hl=en
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== 1 of 1 ==
Date: Sun, Mar 21 2010 10:47 pm
From: 詠嫻

人會瘦，因為他思念別人。
人總是被思念折磨，在思念裡做一頭可憐的流浪狗。

我們每一個人都是被有條件地愛著，
也是有條件地愛著別人。
不必心灰意冷，既然知道世上沒有無條件的愛，
你應該努力使自己更具備條件去愛，
同時也該學習忘記一些條件去愛一個人。

愛情最恐怖的地方，
他愛你，不代表他不會背叛你。
他背叛你，也不代表他不愛你。
不愛上他，就不會因為無法跟他長相廝守而難過。

承諾本來就是男人與女人的一場角力，
有時皆大歡喜，大部分情況卻是兩敗俱傷。

不到最後一刻，千萬別放棄。
最後得到好東西，不是幸運，
有時候，必須有前面的苦心經營，
才有後面的偶然相遇。

有時候，我們愛著的，
不是現實的那個人，而是回憶裡的他。
男人覺得對不起一個女人，
不代表他仍然愛她和思念她 ..
人在回憶的時候，只是回味從前的自己。

有些事情是不可勉強的。
你愛一個人，他不愛你，
不代表你不可愛，不代表你不好，
只能代表他不愛你而已。

有時候，我們願意原諒一個人，
並不是我們真的願意原諒他，
而是我們不想失去他。
不想失去他，惟有假裝原諒他。

一段愛情可以由愛重新開始，
卻不能由原諒重新開始。
我們愛一個人和不愛一個人
往往是因為同一些理由。
時間治療痛苦，也加深了痛苦；
它有時候太長，有時候又太倉促。

感情的事很奇怪。
你很投入的時候，對方很抽離。
你很抽離的時候，對方又偏偏很投入。

男人對女人的傷害，不一定是他愛上了別人，
而是他在她有所期待的時候讓她失望，
在她脆弱的時候沒有扶她一把，
在她成功的時候竟然妒忌她。

愛到極愛，往往變成無情。
恨到極恨，往往不再有恨。
愛情永遠是想像比現實美麗，
相逢如是，告別也如是。
 

 

 

 
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